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A federal appeals court has upheld a lower court ruling that the confession of Brendan Dassey, whose case was part of the Netflix documentary series Making a Murderer, was involuntary. Dassey was found guilty of helping his uncle kill a young woman in 2005, and has been held in a Wisconsin prison.

Women in their 40s at average risk for breast cancer should talk to their health care provider about the risks and benefits of mammography before starting regular screening at that age, according to guidelines released Thursday by the American College of Obstetricians and Gynecologists.

Throngs of mourners paid their final respects to Otto Warmbier Thursday at a public funeral at the high school he attended near Cincinnati. Just four years ago, Warmbier graduated from the school as the salutatorian.

The 22-year-old University of Virginia student was detained in North Korea for 17 months and died on Monday, shortly after he returned to the United States in a coma.

Federal regulators on Thursday said they've identified "the perpetrator of one of the largest ... illegal robocalling campaigns" they have ever investigated.

The Federal Communications Commission has proposed a $120 million fine for a Miami resident said to be single-handedly responsible for almost 97 million robocalls over just the last three months of 2016.

Officials say Adrian Abramovich auto-dialed hundreds of millions of phone calls to landlines and cellphones in the U.S. and Canada and at one point even overwhelmed an emergency medical paging service.

In this week's episode of the show and podcast Invisibilia, we explore what happens when you discover a part of yourself that is very different than who you think you are.

Senate Republicans have spent weeks crafting their latest health care plan to replace the Affordable Care Act in secret

But according to historians Nathan Connolly (@ndbconnolly) and Joanne Freeman (@jbf1755), it’s hardly the first time American politics have been shaped behind closed doors.

The shipping containers that come through the ports of Los Angeles and Long Beach every year would wrap around the Earth two times if you laid them out end-to-end. Those containers are filled with electronics and clothing that are manufactured in places like Asia and then shipped to U.S. retailers.

A Slow And Steady Approach To Chemotherapy

Jun 22, 2017

When doctors treat cancer with chemotherapy, they usually attack the tumor as aggressively as the patient can bear. Then, after a break, they do it again. And again.

But that hard-hitting chemo tactic can have a downside: a few resistant cancer cells may survive, and the cancer can come back.

Impacts And Infrastructure In Extreme Heat

Jun 22, 2017

Commuter planes that can’t fly. Door handles too hot to touch. The heat dome crushing the southwestern U.S. This week puts other heatwaves to shame. We’ll look at dealing with heat in abnormal new normal.

Can Startups Share Their Big City Success?

Jun 22, 2017

The unaffordable urban paradise. Richard Florida says that startups are now tearing cities apart.

For the first time in more than four decades, the Yellowstone grizzly bear is set to lose its federal protections under the Endangered Species Act. Citing a rebound in the bear's population, the U.S. Department of Interior announced its intention Thursday to end these protections and return oversight of the animal's status to the state level.

The agency says the rule to remove the grizzly from the endangered species list will be published "in coming days" and "will take effect 30 days after publication."

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Copyright 2017 NPR. To see more, visit http://www.npr.org/.

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Copyright 2017 NPR. To see more, visit http://www.npr.org/.

AUDIE CORNISH, HOST:

Senate Republicans on Thursday unveiled their plan to repeal and replace the Affordable Care Act — also known as Obamacare. The long-awaited plan marks a big step toward achieving one of the Republican Party's major goals.

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